class Article(models.Model):
  ...
  class Meta:
    permissions = (
      ("publish_article", "Can publish article"),
      ("comment_article", "Can comment article"),
    )

from blog.models import Article
from django.contrib.auth.models import Permission
from django.contrib.contenttypes.models import ContentType
 
content_type = ContentType.objects.get_for_model(article)
permission1 = Permission.objects.create(
  codename='publish_article',
  name='Can publish articles',
  content_type=content_type,
)
 
permission2 = Permission.objects.create(
  codename='comment_article',
  name='Can comment articles',
  content_type=content_type,
)

myuser.user_permissions.add(permission1, permission2, ...)

mygroup.permissions.add(permission1, permission2, ...)

myuser.user_permissions.remove(permission, permission, ...)
myuser.user_permissions.clear()

from django.contrib.auth.models import Permission, User
from django.contrib.contenttypes.models import ContentType
from django.shortcuts import get_object_or_404
 
from myapp.models import BlogPost
 
def user_gains_perms(request, user_id):
  user = get_object_or_404(User, pk=user_id)
  # any permission check will cache the current set of permissions
  user.has_perm('myapp.change_blogpost') 
 
  content_type = ContentType.objects.get_for_model(BlogPost)
  permission = Permission.objects.get(
    codename='change_blogpost',
    content_type=content_type,
  )
  user.user_permissions.add(permission)
 
  # Checking the cached permission set
  user.has_perm('myapp.change_blogpost') # False
 
  # Request new instance of User
  # Be aware that user.refresh_from_db() won't clear the cache.
  user = get_object_or_404(User, pk=user_id)
 
  # Permission cache is repopulated from the database
  user.has_perm('myapp.change_blogpost') # True

from django.contrib.auth.decorators import permission_required
 
@permission_required('polls.can_vote')
def my_view(request):
  ...

from django.contrib.auth.mixins import PermissionRequiredMixin
 
class MyView(PermissionRequiredMixin, View):
  permission_required = 'polls.can_vote'
  # Or multiple of permissions:
  permission_required = ('polls.can_open', 'polls.can_edit')

{{ perms.blog }}

{{ perms.blog.comment_article }}

{% if blog.article %}
  <p>You have permission to do something in this blog app.</p>
  {% if perms.blog.add_article %}
    <p>You can add articles.</p>
  {% endif %}
  {% if perms.blog.comment_article %}
    <p>You can comment articles!</p>
  {% endif %}
{% else %}
  <p>You don't have permission to do anything in the blog app.</p>
{% endif %}

mygroup.permissions = [permission_list]
mygroup.permissions.add(permission, permission, ...)
mygroup.permissions.remove(permission, permission, ...)
mygroup.permissions.clear()

myuser.groups.remove(group, group, ...) #
myuser.groups.clear()